Unit 1 - Transfusion Science Practice 

Indicative Content

In this unit, you will learn about:

Learning Outcomes

You will be expected to:

  1. Determine, explain and classify antibody production with respect to blood group systems. Compare and contrast the major blood group antibodies.
  2. Describe, explain and classify antibody– antigen reactions, the classical complement cascade and antibody-mediated red cell destruction. Examine and categorise causes of intravascular and extravascular red cell destruction.
  3. Describe, explain and categorise the key features of the ABO, Rh and other major blood group systems (Kell, Duffy, Kidd, MNS, Lewis, Lutheran and P1PK)
  4. Describe, explain, demonstrate, interpret and classify automated and manual serological laboratory tests performed in blood transfusion (to include patients and donors).
  5. Examine and solve anomalous serological results for a range of laboratory tests
  6. Describe, explain, justify and contrast the similarities and differences between patient-related and blood donor-related serological testing
  7. Explain, determine and prioritise the principles and practice of Quality Management Systems including quality assurance and quality control in blood transfusion laboratories. 
  8. Determine, explain and predict the hazards associated with various aspects of blood transfusion. Examine the operation of the haemovigilance scheme in the UK
  9. Describe, categorise and explain donor selection criteria in the UK
  10. Describe, categorise and explain processing, testing, storage and specification criteria and issuing of routine blood components supplied by the UK blood services
  11. Describe, explain, categorise and investigate the mechanism of haemolytic disease of the fetus/ newborn. Justify routine antenatal testing requirements

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Unit 2 - Immunohaematology